IPv6 is supported on all Commvault-supported Windows, UNIX and Linux file system, application, and database agents except for the following exceptions:
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1-Touch recovery of clients is not supported with IPv6. 
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For Windows computers, only Microsoft Windows Server 2003 and later Windows versions support IPv6. 
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The Optimize for Concurrent LAN Backups option is not supported for AIX MediaAgents using the IPv6 protocol. 
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To enable IPv6 on Commvault HyperScale X, see Enabling IPv6 Communication on HyperScale Nodes. 
Note
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If a client computer uses IPv6, the CommServe and MediaAgent computers must also use IPv6. 
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If you use IPv6 on a client, make sure that the hostname of the client resolves to the IPv6 address.