Enable immutable snapshots on vault/replica copies to prevent the accidental or intentional snapshot modification or deletion until a set retention time. Once you enable Immutable snapshot, you cannot disable it. This is an irreversible action.
Note
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Creating an immutable snapshot with a vault/replica copy will prevent the creation of normal snapshots with the same copy. All the dependent copies will only be able to create immutable snapshots. 
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Enabling immutable snapshot automatically enables compliance lock on the vault/replica copy. 
Procedure
To enable Immutable snapshot on the vault/replica copy, do the following:
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From the Command Center navigation pane, go to Manage > Plans. The Plans page appears. 
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In the Plan name column, select the backup plan. The Overview page of the backup plan appears. 
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Go to Storage policies tab. 
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In the Copies area, select a Vault/Replica copy on which you want to enable the immutable snapshots. The Configuration page of the snap copy appears. 
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To edit the retention period, do the following: Note You can only set days-based retention to enable immutable snapshots. Extended retention is not supported. - 
In the Retention rules tile, click edit  . .The Edit retention settings page of the snap copy appears. 
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Set the Retention period in terms of number of days. 
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Click Save 
 
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In the General tile, move the Immutable snapshot toggle key to the right. The Configure immutable snapshot dialog box appears. 
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Review and update the retention period of the vault/replica copy and the dependent copies, if any. 
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Click Yes to enable immutable snapshots on all the listed copies.