To exclude specific VM disks from backup operations, you can create a disk filter for a VMware VM group.
From the navigation pane, go to Protect > Virtualization.
The Virtual machines page appears.
On the Hypervisors tab, click the hypervisor.
The hypervisor page appears. The VM groups area displays summary information for any existing VM groups.
On the VM groups tab, click a VM group.
In the Content section, click Manage.
The VM group content dialog box appears.
On the Disk Filters tab, exclude specific VMs or configure a rule to exclude VMs:
To exclude specific VMs, click Browse, and in the Browse virtual machines dialog box, select the VMs.
To exclude a group of VMs, click Add rule, and in the Add disk filter dialog box, configure settings for the filter rule, and then click OK.
For more information and examples, see Add Disk Filter Options for VMware