When performing a full system IntelliSnap backup for a Windows Server 2008 computer, even though the subclient content does not include any local drive, you should exclude any local drive containing system protected files by creating filters for the subclient. On Windows Server 2008, some of the software installation files are considered as system protected files and therefore the local drive where the software is installed must be excluded from the subclient content.
IntelliSnap - Best Practices - Windows File System iDataAgent
Updated